Product ID:DIPHENHYDRAMINE HYDROCHLORIDE
MSDS Date:04/24/1990
FSC:6505
NIIN:00F037775
MSDS Number: BWJVX

Emergency Phone: 615-292-1180/212-789-3535

Info Phone: 212-967-1100/800-445-MSDS

Cage: DO501

Telephone: 212-789-3535

Cage: 0G9K0

DIPHENHYDRAMINE HYDROCHLORIDE

CAS: 147-24-0

RTECS: KR7000000

Fraction By Weight: 100%

LD50 LC50 Mixture:ORAL LD50 (RAT): 500 MG/KG
Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:INHALATION/SKIN: SENSITIZATION. EYES:
SENSITIZATION, ALLERGIC & IRRITATING CONJUNCTIVAL REACTIONS.
INGESTION: URTICARIA, TACHYCARDIA, HEMOLYTIC ANEMIA,
THROMBOCYTOPENIA, ANAPHYLACTIC SHOCK, DEATH BY C ARDIOPULMONARY
ARREST. PRODUCT MAY CROSS THE PLACENTA. ALCOHOL MAY ENHANCE THE
TOXIC EFFECTS.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:THICKENING OF BRONCHIAL SECRETIONS/EPIGASTRIC
DISTRESS/DISTURBED
COORDINATION/DIZZINESS/SLEEPINESS/SEDATION/DRYNESS OF
MOUTH-NOSE-THROAT/TIGHTNESS OF CHEST/WHEEZING/NASAL STUFFINESS/DRUG
RASH/PHOTOSEN SITIVITY/EXCESSIVE
PERSPIRATION/BLURREDVISION/DIPLOPIA/TINNITUS/ACUTE
LABYRINTHITIS/NAUSEA/VOMITING/DIARRHEA (SUPP)
Medical Cond Aggravated by Exposure:INCREASED INTRAOCULAR
PRESSURE/STENOSING PEPTIC ULCER/PYLORODUODENAL
OBSTRUCTION/SYMPTOMATIC PROSTATIC HYPERTROPHY/BLADDER-NECK
OBSTRUCTION/HYPERTENSION/HYPERTHYROIDISM/CARDIOVASCULAR
DISEASE/ASTHMA.

First Aid:INHALATION: REMOVE TO FRESH AIR. GIVE CPR IF NEEDED. KEEP
WARM & QUIET. SKIN: WASH W/SOAP/MILD DETERGENT & LARGE AMOUNTS OF
WATER FOR 15-20 MINS. EYES: WASH IMMEDIATELY W/LARGE AMOUNTS OF
WATER/NORMAL SALINE FOR 15-20 MINS. INGESTION: REMOVE BY
EMESIS/GASTRIC LAVAGE IF CONSCIOUS & NOT CONVULSIVE IF EXTENSIVE
VOMITING HASN'T OCCURED. KEEP HEAD BELOW HIPS DURING VOMITING TO
PREVENT ASPIRATION.(SUPP)

Extinguishing Media:DRY CHEMICAL, CO2, HALON, WATER SPRAY, STANDARD
FOAM. LARGE: WATER SPRAY/FOG, STANDARD FOAM.
Fire Fighting Procedures:MOVE CONTAINERS FROM AREA SAFELY. AVOID
BREATHING VAPORS & DUSTS. KEEP UPWIND. WEAR SCBA W/FULL FACEPIECE
OPERATED IN PRESSURE DEMAND/POSITIVE PRESSURE MODE.
Unusual Fire/Explosion Hazard:DUST-AIR MIXTURES MAY IGNITE/EXPLODE.

Spill Release Procedures:DON'T TOUCH MATERIAL. STOP LEAK SAFELY. SMALL:
TAKE UP W/SAND/OTHER ABSORBENT MATERIAL & PLACE INTO CONTAINERS FOR
LATER DISPOSAL. MOVE CONTAINERS FROM AREA. LARGE: DIKE FAR AHEAD
FOR LATER DISPOSAL. EVACUATE & ISOLATE HAZARD AREA, DENY ENTRY.

Handling and Storage Precautions:STORE AWAY FROM INCOMPATIBLE
SUBSTANCES. KEEP CONTAINER TIGHTLY CLOSED. PROTECT FROM EXPOSURE TO
AIR/LIGHT.

Respiratory Protection:WEAR NIOSH/MSHA APPROVED RESPIRATOR BASED ON
CONTAMINATION LEVELS FOUND IN THE WORK PLACE & MUST NOT EXCEED
WORKING LIMITS OF THE RESPIRATOR.
Ventilation:LOCAL EXHAUST/PROCESS ENCLOSURE SYSTEM.
Protective Gloves:REQUIRED
Eye Protection:SPLASH PROOF GOGGLES & FACE SHIELD
Other Protective Equipment:DUST RESISTANT GOGGLES, IMPERVIOUS CLOTHING,
EYE WASH FOUNTAIN, QUICK DRENCH SHOWER.
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING & SHOES
BEFORE REUSE.
Supplemental Safety and Health
FIRST AID CONT'D: DON'T INDUCE VOMITING IF UNCONSCIOUS. TREAT
SYMPTOMATICALLY/SUPPORTIVELY. OBTAIN MEDICAL ATTENTION IN ALL
CASES. SIGNS/SYMPTOMS CONT'D: CONSTIPATION/ANOREXIA/URINARY
FREQUENCY-DIFFIC ULTY-RETENTION/PALPITATIONS/EXTRA
SYSTOLES/HYPOTENSION/AGRANULOCYTOSIS/EXCITATION/NERVOUSNESS/TREMOR/
EUPHORIA/NEURITIS.

Melt/Freeze Pt:M.P/F.P Text:331-338F
pH:5.5
Solubility in Water:100%
Appearance and Odor:WHITE CRYSTALLINE POWDER W/BITTER TASTE W/NO ODOR.

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZERS.
Stability Condition to Avoid:AIR, LIGHT.
Hazardous Decomposition Products:TOXIC OXIDES OF NITROGEN & CARBON,
TOXIC & CORROSIVE FUMES OF CHLORIDES.

Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.